Items

Items are collectibles used to modify Isaac's attributes, grant or modify tear effects, among other things.

The Ascent of Isaac: Godmode Mod adds 90 items overall, separated into 51 passive items, 34 active items, and 4 elusive story related items.

Passive Items

Icon	Name	Description	Effect	Quality
	Angel Food	Forbidden	+1 Golden Heart. +1 Soul Heart. +0.5 Tears. +20% Gilded chance.
	Birthday Slice	All stats up	+5% Damage, Range, Speed, and Shot Speed. Heals 2 Red health. + 1 Soul Heart. +2.5% additional Damage, Range, Movement Speed, and Shot Speed for each Binge Eater held. If Birthday Mode is activated, all Boss Room items will be Birthday Slices.
	Blood Pudding	This tastes funny...	+5.0 Luck. Randomly applies either Curse of the Lost, Unknown, or Maze whenever a stage does not have an active curse. This is nullified if Isaac holds Black Candle.
	Brass Cross	You feel blessed	+2 Soul Hearts. +25% chance to encounter a floor Blessing.
	Bubble Wand	Bubbly Vengeance	Spawns a wave of bubbles dealing 100% damage on entering a new uncleared room. More bubbles are spawned based on the amount of Red health missing and how many Soul Hearts are held. Bubbles have a 25% chance at 10.0 Luck to spawn larger, bursting into 8 projectiles on popping.
	The Carrot	Sight up?	+1 Red Heart Container. On entering a new stage, reveals either Secret Rooms, special rooms, or the map layout. With more instances of The Carrot, multiple reveals are selected, with 3 instances granting an effect akin to The Mind.
	Celestial Tail	The power of sustainment +3 Keys	All regular Keys are now doubled. +50% chance for any chest to become an Eternal Chest. Grants 3 Keys on picking up.
	Celestial Collar	The power of life	Boss items, shop items and treasure room items have a 15% chance to be replaced with 1up!. Grants a stacking 110% Damage multiplier per extra life.
	Crimson Solution	Fragile Treatment	Grants a random syringe item effect on entering each room. When fatal damage is taken, prevent death once and this item is removed and converted into a Broken Syringe trinket.
	Crossbones	Break for protection	Grants a shield for 3 seconds after killing 4 enemies.
	Cup O' Nog	Nice and Hearty	+2 Red Heart Container. Heals 4 Red health. +3.0 Luck. If Christmas Mode is activated, all players will get this item.
	Dad's Key Ring	Which one again?	A stacking chance builds up to activate Dad's Key when this item procs. The chance starts at 0% and grows by: Clearing rooms (+12.5%) Taking Damage (+33.4%) When clearing a room, the chance is attempted and if successful uses Dad's Key and the chance is reset to 0%. Otherwise, does nothing (Random key trinket displayed). When taking damage, if the chance is currently above 100% then Dad's Key is used and the chance is reset to 0%.
	Devil's Food	The Lie	+2 Black Hearts. +1.0 Damage.
	Divine Approval	The heart of gold hurts the most	+0.25 Tears per Golden Heart. +3 Soul Hearts. Full Golden Hearts on pickup. +1 Golden Heart per floor.
	Divine Wrath	May your power last a thousand lifetimes	Gain +3% Damage when clearing a room without taking damage, up to +100% Damage. When damage is taken: damage all enemies in the room for (current buff %) of their Max Health. The buff percentage is reset to +0% Damage.
	Edible Soul	He'll come for you when you're gone	+1 Black Heart. When you would die with no lives remaining, you get revived with the following effects: Gain Flight. 3 Charmed Furnace Knights spawn. Health gets set to 1 Black Heart. +3 Broken Hearts.
	Fatal Attraction	Go out in your own style	+1 Black Heart. -3 Red health. At the start of each floor, there are 3 options to exchange a 10% buff to one stat for a 7.5% debuff in another stat.
	Feather Duster	Cleaning Services	+0.1 Movement Speed. Prevents negative door hazards from spawning. Walking over a web will break it. Walking over a Sticky Nickel cleans it. Walking over a Bedroom carpet cleans it.
	Forbidden Knowledge	Paid fulfillment	When picking up a Red Heart, spawn either a Bomb, key, Coin, or nothing. The odds for the bomb or key go up the larger the Red heart is (i.e. a Double Red Heart is more likely than a Half Red Heart).
	Foreign Treatment	Experimental Outcomes	Grants a random stat multiplier to each stat at the start of each stage. Each multiplier is rerolled on entering a new stage, and the more instances of this item held, the odds for better multipliers goes up.
	Four Leaf Clover	Luck = Power	+2.0 Luck. +(0.5 × (Luck+2)) Damage. +(0.25 × (Luck+2)) Tears.
	Fruit Salad	Healthy Snack	+1 Red Heart Container. +2 Red Hearts. +1 Soul Heart. Spawns 8 random Fruits pickups, each granting a small, temporary buff.
	Gangrene	Rotten flecks	Leave a trail of tears that are 10% of your Damage stat, with a chance for the tear to apply a poison effect.
	Gold Plated Battery	Money = Charge	Hold the active item button to spend 5 Coins on 1 charge of your active item.
	Crown of Gold	Money, money, money!	Midas Freeze an enemy in a new, uncleared room for 7.5 seconds. +1.0 Luck for every 25 Coins, up to +3.0 Luck at 99 Coins. When damage is taken, money is lost: 5 × (DamageTaken) + RandomBetween(1,3)
	Cloth of Gold	Seeping power	Evenly splits your damage across all enemies of the same type within the room, and grants +25% damage if Cloth on a String is held. +25% Damage. +25% Gilded chance.
	Greedy Glance	All the eye can see is yours	When your tears touch a Bomb, key, or Coin, collect the pickup. When your tears touch an unlocked chest, open the chest.
	Heart Arrest	It hurts...	+0.25 Tears. Tears now fire in a heartbeat pattern.
	Hot Potato!	Hot! Hot! Hot!	3% + 1% per Luck chance to hurl a flaming potato instead of firing a tear. This potato deals (Damage × 1.5 + 5) contact damage and burns for 10% of this damage. The potato then breaks into chunks dealing 10% of the potato's damage each, with each one targeting a nearby enemy within a large radius. The maximum chance to hurl a flaming potato with 1 copy of this item is 20% at 17 luck. However, the maximum chance goes up by 20% per additional copy, at the cost of an additional 20 luck required for max chance. In example, 5 copies of Hot Potato! allows you to reach 100% chance at 97 luck.
	Hysteria	Easily overwhelmed	+0.05 Fire Delay per living enemy or boss. +0.25 Tears per living boss.
	Jack-of-all-Trades	Become anything	Counts as 1 item towards every vanilla and Godmode Transformation.
	The Ladle	Slurp with love!	+1 Red Heart Container. +0.1 Movement Speed. +0.1 Movement Speed after taking damage, stackable up to 5 times. On entering a new stage, the stackable bonus is reset.
	Larval Therapy	My eyes itch	+33.3% chance to spawn a Winged Spider when an enemy dies. This is set to +100% if playing Recluse. Winged spiders created this way target the enemy with the highest health and die after applying enough damage.
	Late Delivery	A little later than expected	+0.5 Tears. After dealing 2500 damage, an angelic baby familiar will grant a random item from the current room's item pool. This concerns everyone, not just players owning the item. More items can be granted, but at an additional 5000 damage dealt each iteration.
	Marshall Scarf	Be strong in the face of evil	+0.5 Fire Delay when held before the Womb. +0.75 Fire Delay when held within the Womb. +1.0 Fire Delay when held after the Womb.
	Morphine	I can't feel anything!	+10% Damage. −20% Speed. 30% Chance to negate any damage taken. +2 Broken Hearts.
	Nirvana	The darkness is weakened	All enemies spawn with 80% Max Health. This effect can stack.
	Nosebleed	I think it's stopping!	Grants a 150% Damage multiplier whenever a room is entered, gradually fading over the course of 8 seconds.
	Party Hat	Join the Party	Only shows up if Birthday Mode is activated. Gives you a nice party hat cosmetic. That's pretty much it...
	Prayer Mat	Clear your mind	The first time you stand still for 10 seconds each uncleared room grants you half a Soul Heart along with a Crack The Sky beam, dealing damage to nearby enemies.
	A Second Thought	Time means nothing now	+0.2 Movement Speed. Passage to Blue Womb and Boss Rush door are always open. Call of the Void no longer can spawn naturally.
	Sharing is Caring	We feel invincible!	All non-orbital familiars operate 33% faster.
	Soft Serve	Spilled Milk + HP Up	+1 Soul Heart. +2 Additional Soul Hearts if Red Health is either full or empty. Grants a chance to spawn colored creep on attack, each color with a unique effect. White creep: Freezes enemies. Pink creep: Homes on enemies. Red creep: Applies Bleed to enemies. Light Brown creep: Spawns a Linger Bean cloud if the enemy is killed by the creep. Dark Brown creep: Double damage and size, half range creep.
	Soul Food	Good for you	+2 Soul Hearts. +1 Luck.
	Sugar!	I.. Need.. MORE!	Grants small increments of Fire Delay upgrades and Damage multipliers each time it is picked up. −1 Red Heart Container. The next three non-quest items you see have a 50% chance to become Sugar!.
	Taenia	Brain power up	+5 Range. +0.5 Tears. −0.25 Shot Speed. You can create a path for your tears to follow by continuously changing fire directions before releasing all fire keys.
	Cloth on a String	Seeping Bleeding	+5% damage dealt on an enemy for each other instance of the same enemy in the room. +1% chance for any non-quest item to transform into Cloth of Gold if it is not held by the same player.
	Tramp of Babylon	Strength with a cost...	Grants a damage multiplier to counteract HP scaling. After taking damage for the first time in a room, monsters are split into two and bosses regain 50% of their missing health.
	Uncommon Cough	I-I-I'm fINE!!	Replaces tears with a spurt of tears. 50% of these tears will not share any tear effects collected throughout the run, and each tear deals a modified amount of damage based on its size. Spurts increase in quantity, speed, and distance the longer you hold the fire button.
	Vajra	Strike down those who break your spirit	Strike all enemies with electricity when you take damage, each laser dealing 200% + 10 Damage.
	War Banner	Wrath = Power +5 Bombs	Placing a Bomb spawns a banner that grants a small stat upgrade while you stand in its radius. Red is +20% Damage. Blue is +0.25 Tears. Yellow is +0.1 Shot Speed. Grants 5 Bombs on picking up.
	Wings of Betrayal	Gain with Pain!	+2.5 Damage and gain Flight after taking damage in a room.

Active Items

Icon	Name	Charges	Description	Effect	Quality
	Abraham's Map		The odds are in your favor!	If there is a pedestal item below quality 4 in the room, converts it to a random quality 4 item from any pool. If there is no pedestal items that qualify to be buffed, creates a random item from the current room's item pool instead. You only get 2 uses of this item per instance picked up; once you run out of uses, the item is destroyed.
	Adramolech's Blessing		Hold to my word and your time shall come	Charges negate damage taken. One charge gained for every 4 marked champion enemies killed. +10% chance for marked champions per charge. +10% chance for Devil items to be rerolled into a higher quality item. When used, grants a permanent small all stat up. +0.20 Speed +0.27 Tears +0.99 Damage +0.03 Shot Speed +1.00 Luck
	Angry Apple Juice		What'd I do?	Heals every player for half a Red Heart. Grants the user +20% +1.0 Damage for the room. Brief pixilation effect occurs every other second for the duration of the room.
	Arcade Ticket		Game time?	If an unentered Arcade Room is on the stage, teleport to it. Otherwise, if used in an arcade: 90% chance to spawn a random pickup/collectible. 10% chance to spawn a red coin. If used outside of an arcade, spawns 1 Penny.
	Baptismal Cross		Become reborn in the water!	Spawn a flurry of tears from the sky above the player, dealing between 50% to 150% damage per tear.
	Black Mushroom		It smells sleepy	+3 Soul Hearts. −1 Red Heart Container. Grants full Red Hearts. Rerolls the current floor after you leave the room that Black Mushroom was used in.
	Burnt Diary		As we burn another page	On use, spawns 5 burning pages, each dealing 30 burn damage and 5 contact damage once. Pages persist until they deal damage, at which point they are destroyed.
	Impending Doom		Time is running out for all	+1 Broken Heart whenever a new stage is entered. On use: Deals 10 damage or 25% Max Health to all enemies in the room, whichever is greater.
	Cash Dice		Reroll your options	Selects the nearest item or shop item. If it is a shop item, splits it into two new shop items. If it is not a shop item, converts the item into a shop item for sale. Can be used up to 5 times in 1 room.
	Celestial Paw		Slash them in your soul	On use: −1 Red Heart Container. All non-boss enemies are converted to half a soul heart. Boss enemies are dealt damage equal to 25% of their Max Health. If they are killed by this, they also get converted to half a Soul Heart.
	Dad's Balloon	4 s	It doesn't hold water very well	On use, does one of the following randomly: Spawn a pool of Holy Water creep. Fire a ring of 4, 8, or 16 tears.
	Diya		Evil spirits, wane!	On use, permanently applies weakness to nearby enemies.
	Dragon Fruit		You feel stronger	On use: Heals half a Red Heart for all players. Grants a random medium, temporary stat buff. Buffs the effects of Fruits stat buffs.
	Fuzzy Dice		A collectible!	Redistributes 33% of current Coins, Keys, and Bombs randomly.
	Ghanta		Ring for protection	On use: −1 Red Heart Container. Brings you down to Half a Red Heart, converting the health lost into Soul Hearts.
	Anguish Jar		Let it all out!	Creates a controllable Hush Laser, dealing 40 damage per tick. This laser persists between rooms and lasts for roughly 10 seconds.
	Blaze's Head		I wish..	On use: +25% Damage. −10% Fire Rate. −5% Movement Speed. Can be used up to 5 times in the same room for a stackable effect.
	Odd Dice		Reroll your destiny?	Rerolls items in the room. 33% chance to hide a rerolled item. +10% chance after each use for the Odd Dice to break into 2 Dice Shards.
	Opia		Feel their soul	On use, throw your soul into an enemy to possess that enemy for the room, charming all instances of that enemy and appearing as that enemy for the room.
	Papal Cross		True command	Teleports the player to a special Angel or Devil Room, depending on the current state of the item. This room has enemies, but also has a free Angel/ Devil item (and a second for those with debug or Blessing of Patience). When holy: the lower your Angel room chance is, the more likely it gets converted to the unholy variant. When unholy: 50% chance to be destroyed, otherwise the same chance as your Angel room chance to be rerolled into the holy variant.
	Portable Confessional		Atone at home!	On use, hurts the player for Half a Red Heart. When an Angel Room is entered, fully charges the item. If used with Broken Hearts in an Angel Room, removes 3 Broken Hearts and destroys the item. If used in an Angel Room without Broken Hearts or outside of an Angel Room, spawns 1 Soul Heart.
	Qur'an		Cleanse your soul	Removes all Black Hearts, granting +1.5 Soul Hearts per black heart. Instantly kills Mom and Mom's Heart. Kills you when used against Satan.
	Radiance Orb	12 s	Show them the light	Creates a ring of spectral, piercing, Godhead tears that rotate around you for a period of time, inflicting 200% + 20.0 Damage each on contact.
	Red Juice	0.67 s	The cool-aid	+1 Luck. +0.05 Movement Speed. Slightly distorts vision, akin to Wavy Cap. These effects can be stacked up to 20 times to increase the potency of the item. The potency decays at a rate of 1 use every 30 seconds, and decays by 1 use every room clear.
	Book of Saints		Look up to the hearts of gold	On use: +2 Golden Hearts. +1 Soul Heart. +15% Gilded chance.
	Seraphim Warhorn		They hear your call	Summons a charmed Bloody Uriel to assist you for the duration of the room.
	Tecpatl		Loss = Life	On use: Become invincible for 20 seconds, persisting between rooms. +1 Broken Heart. −1 Red Heart Container.
	Child's Trophy	2 floors	Prove your strength to them	Activates a 600% Damage multiplier and +3 Tears when used for the duration of the room.
	Fractal Key	1 s	Life unlocked	When used, grants 1 Broken Heart and 1 Faithless Heart as well as following this formula for a chance to replace pickups with a golden variant (called Gilded chance): N = total number of uses X = granted chance if N ≤ 0: 0% if N < 5: 10% − (N − 1) * 2% if N ≥ 5: 5% ÷ (N − 3) So in example, total chance to replace a pickup is as follows per use: - (10% → 20% → 28% → 34% → ...<39%) While held, all golden pickups are replaced with 3 random versions of that pickup. if another golden one is rolled without this bonus, this could lead to a chain reaction, but the chance this item grants does not apply to this split. The chance that this item grants will decrease by 1% for each new room entered. When you re-use the item, the chance that will be added will be the compounded chance (similar to the way that fruit stat buffs work). If using this item would kill the player via broken/faithless hearts, instead turns this item into the Inverse Key and causes the player to explode.
	Inverse Key	1 s	Life restored	When used, sets your Gilded chance to 0%. Whatever your Gilded chance was before this reset will dictate how strong the effects of this item are. When used at 100% Gilded chance, removes 8 Broken hearts and 8 Faithless hearts from the user. When used at 0% chance, removes none of each. Each 12.5% of Gilded chance grants 1 more Broken and Faithless heart removed. In addition to this reset, this item turns back into the Fractal Key and the player explodes. While held, all golden pickups are replaced with 3 random versions of that pickup (if another golden one is rolled without this bonus, this could lead to a chain reaction but the chance this item grants does not apply to this split). The chance that this item grants will decrease by 0.5% for each new room entered. When you re-use the item, the chance will go back to full strength (similar to the way that fruit stat buffs work).

Familiars Items

Icon	Name	Description	Effect	Quality
	Fallen Guard	The heat has marked you	Summons a mini Furnace Knight to fight for you, dealing 15% + 1.3 Damage each tick. The longer he is on an enemy, the faster and more accurate he locks on to them.
	Fruit Flies	They've got the good stuff	Summons 3 Fruit Flies to grow with you. Each room clear, each fly gains a stacking 3% chance to burst into a random fruit, spawning a sleeping baby Fruit Fly. Sleeping Fruit Flies will wake up after 2 rooms.
	Hellfiah Saus	What a dumpster fire	A familiar that can breathe fire. The fire gets stronger the longer you charge the attack for, but can be released with partial charge. After a certain charge time, begins flashing blue which indicates a couple longer lasting, weaker blue flames will spawn at the start of the next attack.
	Holy Chalice	Give me the strength to fight	Stackable +10% Damage per room cleared without taking damage, up to +40% Damage. Resets to +0.0 Damage when damage is taken. The cup fills up more based on the current bonus.
	Pair of Cans	I hear mommy!	Grants 4 orbital familiars at the start of each room that each block 1 projectile.

Quest Items (Spoilers)

Icon	Name	Description	Effect	Quality
	Blood Key	Your fate is sealed	Received from the Stifled Gatekeeper in Sheol/ Cathedral for granting an Angel/ Devil item (respectively) to the Gatekeeper. Allows entry to The Ivory Palace after clearing the Cathedral or Sheol.
	Vessel of Purity	Reveal the truth from within	If retained after the first phase of The Fallen Light is defeated, grants access to a hidden phase of The Fallen Light and modifies The Sign's starting stats. If damaged while fighting The Fallen Light: Explodes, turning into Cracked Vessel of Purity.
	Cracked Vessel of Purity	Reveal the truth from within	If retained after the first phase of The Fallen Light is defeated, grants access to a hidden phase of The Fallen Light and modifies The Sign's starting stats. If damaged while fighting The Fallen Light: Explodes, turning into Bloodied Vessel of Purity. +0.5 Tears. +1.0 Damage.
	Bloodied Vessel of Purity	Reveal the truth from within	If retained after the first phase of The Fallen Light is defeated, grants access to a hidden phase of The Fallen Light and modifies The Sign's starting stats. If damaged while fighting The Fallen Light: Explodes and gets destroyed, losing access to the hidden phase of The Fallen Light. +1.0 Tears. +3.0 Damage.

Tainted Characters Starting Active Items

Icon	Name	Charges	Description	Effect	Quality
	Mom's Wish	1 floor	Fulfill her dreams	When used as Tainted Lost, spawns a Holy Card and grants a permanent −5% all stats down. When used as a character other than Tainted Lost, spawns a Soul Heart on use. Charges once per stage.
	Delusion	3.75 s	Reassociate	Converts your delirious eyes into a delirious halo and transforms into Oblivion. The delirious halo will negate damage taken, closing the following quantity of eyes: ceil(1.5 × DamageTaken) While your halo is up: +2.5% Range per Delirious Eye.
	Oblivion	3.75 s	Dissociate	Converts your delirious halo into delirious eyes and transforms into Delusion. While your halo is down: +5% Damage per Delirious Eye. +10% Fire Rate. −20% Range.
	Adramolech's Fury	100	Hold to my word and your time shall come	Charges negate damage taken, losing 20 charge on hit. Each charge grants a small all stats up. 50% chance for each enemy to become a marked champion. Charges either when: a marked champion or any boss dies, converting them into charge based on Max Health. any non- Angel Item is picked up, converting items into charge based on quality. On use, you are teleported to a unique Devil Room layout, granting 3 free Devil items with Black Hearts and Soul of Isaac in the room.
	Reclusive Tendencies	12 s	They are your friends	On use: All small spiders and Winged Spiders are charmed for 10 seconds. Spawns a toxic Winged Spider for each Winged Spider active, dealing damage to the healthiest enemy in the room.
	Vengeful Dagger	4 s	Everlasting Wrath	When used, throws the dagger in the fire direction or the movement direction if not firing. Each dagger deals 200% Damage, and if the room is re-entered, deals an additional 600% Damage when the enemy respawns.
	Golden Stopwatch		Feel the rewards	Spawns 5 Pennies, makes the room gold. Until you leave the room, each coin shot turns back into coin pickups, no matter if they touched an enemy or not.